State Street® SPDR® S&P® Pharmaceuticals ETF (XPH) is a SPDR ETF with a 0.35% expense ratio, 63 holdings and $450MM in net assets. Largest sector: Healthcare (100%).
Fee
0.35%
expense ratio
Net assets
$450MM
Launched
Jun 19, 2006
Holdings
63
as of Oct 22, 2026
Top 10 weight
24.2%
largest ten holdings
Largest sector
Healthcare
100.0%
Yield
30-day SEC 0.35% · TTM 0.43%
as of Oct 22, 2026
Benchmark
S&P Pharmaceuticals Select Industry
XPH's holdings are as of Oct 22, 2026.
Healthcare
100.0%
1
XERS
Xeris Biopharma Holdings
2.83%
2
MANE
VeraDermics
2.79%
3
PCRX
Pacira BioSciences
2.55%
4
AMRX
Amneal Pharmaceuticals
2.39%
5
LLY
ELI LILLY
2.33%
6
MAZE
Maze Therapeutics
2.33%
7
PRGO
Perrigo
2.29%
8
VTRS
VIATRIS
2.25%
9
ZTS
ZOETIS
2.25%
10
PFE
PFIZER
2.20%
11
LGND
Ligand Pharmaceuticals
2.15%
12
RPRX
ROYALTY PHARMA
2.12%
13
ANIP
ANI Pharmaceuticals
2.10%
14
INDV
Indivior Pharmaceuticals
2.04%
15
PBH
Prestige Consumer Healthcare
2.04%
16
OGN
Organon
2.02%
17
SEPN
Septerna
2.02%
18
JNJ
JOHNSON + JOHNSON
2.01%
19
MRK
MERCK
2.01%
20
SUPN
Supernus Pharmaceuticals
2.01%
21
INVA
Innoviva
2.00%
22
COLL
Collegium Pharmaceutical
1.98%
23
BMY
BRISTOL-MYERS SQUIBB
1.97%
24
ELAN
Elanco Animal Health
1.94%
25
DFTX
DEFINIUM THERAPEUTICS
1.91%
1–25 of 63
Funds listed by how much of their largest holdings they share with XPH — not a ranking.
Data from SPDR; prices and returns from market data. Page updated October 29, 2026. Holdings and figures change over time. For information only — not investment advice.