iShares Biotechnology ETF (IBB) is a iShares ETF with a 0.44% expense ratio, 243 holdings and $10.7B in net assets. Largest sector: Healthcare (100%).
Fee
0.44%
expense ratio
Net assets
$10.7B
Launched
Feb 5, 2001
Holdings
243
as of Oct 22, 2026
Top 10 weight
50.9%
largest ten holdings
Largest sector
Healthcare
100.0%
Yield
30-day SEC -0.15% · TTM 0.16%
as of Sep 30, 2026
Benchmark
ICE Biotechnology Index
IBB's holdings are as of Oct 22, 2026.
Healthcare
100.0%
1
GILD
GILEAD SCIENCES
8.56%
2
AMGN
AMGEN
8.29%
3
VRTX
VERTEX PHARMACEUTICALS
7.83%
4
REGN
REGENERON PHARMACEUTICALS
5.72%
5
MRNA
MODERNA
5.22%
6
NTRA
Natera
3.81%
7
ARGX
ARGENX
3.43%
8
ILMN
ILLUMINA
2.86%
9
BIIB
BIOGEN
2.62%
10
RVMD
Revolution Medicines
2.55%
11
ONC
BEONE MEDICINES LTD-ADR
2.27%
12
ALNY
Alnylam Pharmaceuticals
2.14%
13
UTHR
United Therapeutics
1.71%
14
INCY
INCYTE
1.66%
15
GMAB
GENMAB A/S SP ADR ADR
1.56%
16
INSM
Insmed
1.44%
17
ROIV
Roivant Sciences Ltd.
1.38%
18
CRL
CHARLES RIVER LABORATORIES
1.13%
19
EXEL
Exelixis
1.10%
20
ASND
Ascendis Pharma A/S
1.06%
21
MEDP
Medpace Holdings
1.04%
22
NBIX
Neurocrine Biosciences
1.01%
23
HALO
Halozyme Therapeutics
0.99%
24
BBIO
Bridgebio Pharma
0.84%
25
TECH
BIO TECHNE
0.80%
1–25 of 243
Funds listed by how much of their largest holdings they share with IBB — not a ranking.
Data from iShares; prices and returns from market data. Page updated October 29, 2026. Holdings and figures change over time. For information only — not investment advice.